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Kinase Regulation by Hydrophobic Spine Assembly in Cancer
A new model of kinase regulation based on the assembly of hydrophobic spines has been proposed. Changes in their positions can explain the mechanism of kinase activation. Here, we examined mutations in human cancer for clues about the regulation of the hydrophobic spines by focusing initially on mut...
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| Publicat a: | Mol Cell Biol |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4295384/ https://ncbi.nlm.nih.gov/pubmed/25348715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00943-14 |
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