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Conformationally Constrained and Nanoparticle Targeted Paclitaxels

Paclitaxel (Taxol(®)) is one of the most important anticancer agents developed over the last 30 years. Its primary mechanism of action is by interaction with the cellular protein tubulin, causing irreversible polymerization to microtubules. A detailed knowledge of this crucial interaction is thus of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pure Appl Chem
Egile Nagusiak: Kingston, David G. I., Tamarkin, Lawrence, Paciotti, Giulio F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295212/
https://ncbi.nlm.nih.gov/pubmed/25598555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1351/PAC-CON-11-09-02
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