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Conformationally Constrained and Nanoparticle Targeted Paclitaxels

Paclitaxel (Taxol(®)) is one of the most important anticancer agents developed over the last 30 years. Its primary mechanism of action is by interaction with the cellular protein tubulin, causing irreversible polymerization to microtubules. A detailed knowledge of this crucial interaction is thus of...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Pure Appl Chem
Päätekijät: Kingston, David G. I., Tamarkin, Lawrence, Paciotti, Giulio F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295212/
https://ncbi.nlm.nih.gov/pubmed/25598555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1351/PAC-CON-11-09-02
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