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Targeting of albumin-embedded paclitaxel nanoparticles to tumors

We have used tumor-homing peptides to target abraxane, a clinically approved paclitaxel-albumin nanoparticle, to tumors in mice. The targeting was accomplished with two peptides, CREKA, and LyP-1 (CGQKRTRGC). Fluorescein (FAM)-labeled CREKA-abraxane, when injected intravenously into mice bearing MDA...

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Detalhes bibliográficos
Main Authors: Karmali, Priya Prakash, Kotamraju, Venkata Ramana, Kastantin, Mark, Black, Matthew, Missirlis, Dimitris, Tirrell, Matthew, Ruoslahti, Erkki
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824435/
https://ncbi.nlm.nih.gov/pubmed/18829396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2008.07.007
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