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Targeting atherosclerosis by using modular, multifunctional micelles

Subtle clotting that occurs on the luminal surface of atherosclerotic plaques presents a novel target for nanoparticle-based diagnostics and therapeutics. We have developed modular multifunctional micelles that contain a targeting element, a fluorophore, and, when desired, a drug component in the sa...

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Detalhes bibliográficos
Main Authors: Peters, David, Kastantin, Mark, Kotamraju, Venkata Ramana, Karmali, Priya P., Gujraty, Kunal, Tirrell, Matthew, Ruoslahti, Erkki
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689312/
https://ncbi.nlm.nih.gov/pubmed/19487682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903369106
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