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Vascular changes in tumors resistant to a vascular disrupting nanoparticle treatment

Anti-angiogenic and vascular disrupting therapies rely on the dependence of tumors on new blood vessels to sustain tumor growth. We previously reported a potent vascular disrupting agent, a theranostic nanosystem consisting of a tumor vasculature-homing peptide (CGKRK) fused to a pro-apoptotic pepti...

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Détails bibliographiques
Publié dans:J Control Release
Auteurs principaux: Sharma, Shweta, Mann, Aman P, Mölder, Tarmo, Kotamraju, Venkata Ramana, Mattrey, Robert, Teesalu, Tambet, Ruoslahti, Erkki
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819600/
https://ncbi.nlm.nih.gov/pubmed/29030222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2017.10.006
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