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Vascular changes in tumors resistant to a vascular disrupting nanoparticle treatment

Anti-angiogenic and vascular disrupting therapies rely on the dependence of tumors on new blood vessels to sustain tumor growth. We previously reported a potent vascular disrupting agent, a theranostic nanosystem consisting of a tumor vasculature-homing peptide (CGKRK) fused to a pro-apoptotic pepti...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Sharma, Shweta, Mann, Aman P, Mölder, Tarmo, Kotamraju, Venkata Ramana, Mattrey, Robert, Teesalu, Tambet, Ruoslahti, Erkki
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819600/
https://ncbi.nlm.nih.gov/pubmed/29030222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2017.10.006
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