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Visual and functional demonstration of growing Bax-induced pores in mitochondrial outer membranes
Bax induces mitochondrial outer membrane permeabilization (MOMP), a critical step in apoptosis in which proteins are released into the cytoplasm. To resolve aspects of the mechanism, we used cryo-electron microscopy (cryo-EM) to visualize Bax-induced pores in purified mitochondrial outer membranes (...
Shranjeno v:
| izdano v: | Mol Biol Cell |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The American Society for Cell Biology
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4294680/ https://ncbi.nlm.nih.gov/pubmed/25411335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-11-0638 |
| Oznake: |
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