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The catalytically inactive tyrosine phosphatase HD-PTP/PTPN23 is a novel regulator of SMN complex localization

The survival motor neuron (SMN) complex fulfils essential functions in the assembly of snRNPs, which are key components in the splicing of pre-mRNAs. Little is known about the regulation of SMN complex activity by posttranslational modification despite its complicated phosphorylation pattern. Severa...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Husedzinovic, Alma, Neumann, Beate, Reymann, Jürgen, Draeger-Meurer, Stefanie, Chari, Ashwin, Erfle, Holger, Fischer, Utz, Gruss, Oliver J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294665/
https://ncbi.nlm.nih.gov/pubmed/25392300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-06-1151
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