HD-PTP Is a Catalytically Inactive Tyrosine Phosphatase Due to a Conserved Divergence in Its Phosphatase Domain

BACKGROUND: The HD-PTP protein has been described as a tumor suppressor candidate and based on its amino acid sequence, categorized as a classical non-transmembrane protein tyrosine phosphatase (PTP). To date, no HD-PTP phosphorylated substrate has been identified and controversial results concernin...

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Main Authors: Gingras, Marie-Claude, Zhang, Yu Ling, Kharitidi, Dmitri, Barr, Alastair J., Knapp, Stefan, Tremblay, Michel L., Pause, Arnim
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661844/
https://ncbi.nlm.nih.gov/pubmed/19340315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005105
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