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Macrophage Fusion Is Controlled by the Cytoplasmic Protein Tyrosine Phosphatase PTP-PEST/PTPN12

Macrophages can undergo cell-cell fusion, leading to the formation of multinucleated giant cells and osteoclasts. This process is believed to promote the proteolytic activity of macrophages toward pathogens, foreign bodies, and extracellular matrices. Here, we examined the role of PTP-PEST (PTPN12),...

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Hlavní autoři: Rhee, Inmoo, Davidson, Dominique, Souza, Cleiton Martins, Vacher, Jean, Veillette, André
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700098/
https://ncbi.nlm.nih.gov/pubmed/23589331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00197-13
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