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Rapid Lead Discovery Through Iterative Screening of One Bead One Compound Libraries

[Image: see text] Primary hits that arise from screening one bead one compound (OBOC) libraries against a target of interest rarely have high potency. However, there has been little work focused on the development of an efficient workflow for primary hit improvement. In this study, we show that by c...

詳細記述

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書誌詳細
出版年:ACS Comb Sci
主要な著者: Gao, Yu, Amar, Sabrina, Pahwa, Sonia, Fields, Gregg, Kodadek, Thomas
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2014
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294594/
https://ncbi.nlm.nih.gov/pubmed/25434974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/co500154e
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