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Incorporation of Heterocycles into the Backbone of Peptoids to Generate Diverse Peptoid-Inspired One Bead One Compound Libraries

Combinatorial libraries of peptoids (oligo-N-substituted glycines) have proven to be useful sources of protein ligands. Each unit of the peptoid oligomer is derived from 2-haloacetic acid and a primary amine. In order to increase the chemical diversity available in peptoid libraries, we demonstrate...

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Autors principals: Aditya, Animesh, Kodadek, Thomas
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379557/
https://ncbi.nlm.nih.gov/pubmed/22320121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/co200195t
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