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A Cleavable Scaffold Strategy for the Synthesis of One-Bead One-Compound Cyclic Peptoid Libraries That Can Be Sequenced By Tandem Mass Spectrometry

Many macrocyclic depsipeptides or related compounds have interesting medicinal properties and often display more favorable pharmacokinetic properties than linear analogues. Therefore, there is considerable interest in the development of large combinatorial libraries of macrocyclic peptidomimetic com...

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Autors principals: Simpson, Levi S., Kodadek, Thomas
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379548/
https://ncbi.nlm.nih.gov/pubmed/22736872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2012.02.112
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