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Novel Peptide Ligands of RGS4 from a Focused One-Bead, One-Compound Library

Regulators of G Protein Signaling (RGS) accelerate GTP hydrolysis by Gα subunits and profoundly inhibit signaling by G protein-coupled receptors. The distinct expression patterns and pathophysiologic regulation of RGS proteins suggest that inhibitors may have therapeutic potential. We previously rep...

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Detalhes bibliográficos
Main Authors: Roof, Rebecca A., Sobczyk-Kojiro, Katarzyna, Turbiak, Anjanette J., Roman, David L., Pogozheva, Irina D., Blazer, Levi L., Neubig, Richard R., Mosberg, Henry I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917810/
https://ncbi.nlm.nih.gov/pubmed/18637987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2008.00687.x
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