Conformation Determines the Seeding Potencies of Native and Recombinant Tau Aggregates

Intracellular Tau inclusions are a pathological hallmark of several neurodegenerative diseases, collectively known as the tauopathies. They include Alzheimer disease, tangle-only dementia, Pick disease, argyrophilic grain disease, chronic traumatic encephalopathy, progressive supranuclear palsy, and...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Falcon, Benjamin, Cavallini, Annalisa, Angers, Rachel, Glover, Sarah, Murray, Tracey K., Barnham, Luanda, Jackson, Samuel, O'Neill, Michael J., Isaacs, Adrian M., Hutton, Michael L., Szekeres, Philip G., Goedert, Michel, Bose, Suchira
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294473/
https://ncbi.nlm.nih.gov/pubmed/25406315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.589309
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