Short Fibrils Constitute the Major Species of Seed-Competent Tau in the Brains of Mice Transgenic for Human P301S Tau

The interneuronal propagation of aggregated tau is believed to play an important role in the pathogenesis of human tauopathies. It requires the uptake of seed-competent tau into cells, seeding of soluble tau in recipient neurons and release of seeded tau into the extracellular space to complete the...

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Detaylı Bibliyografya
Yayımlandı:J Neurosci
Asıl Yazarlar: Jackson, Samuel J., Kerridge, Caroline, Cooper, Jane, Cavallini, Annalisa, Falcon, Benjamin, Cella, Claire V., Landi, Alessia, Szekeres, Philip G., Murray, Tracey K., Ahmed, Zeshan, Goedert, Michel, Hutton, Michael, O'Neill, Michael J., Bose, Suchira
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2016
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719013/
https://ncbi.nlm.nih.gov/pubmed/26791207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3542-15.2016
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