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Quantitative propagation of assembled human Tau from Alzheimer's disease brain in microfluidic neuronal cultures

Tau aggregation and hyperphosphorylation is a key neuropathological hallmark of Alzheimer's disease (AD), and the temporospatial spread of Tau observed during clinical manifestation suggests that Tau pathology may spread along the axonal network and propagate between synaptically connected neur...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Biol Chem
Κύριοι συγγραφείς: Katsikoudi, Antigoni, Ficulle, Elena, Cavallini, Annalisa, Sharman, Gary, Guyot, Amelie, Zagnoni, Michele, Eastwood, Brian J., Hutton, Michael, Bose, Suchira
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7489902/
https://ncbi.nlm.nih.gov/pubmed/32699110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013325
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