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Quantitative propagation of assembled human Tau from Alzheimer's disease brain in microfluidic neuronal cultures
Tau aggregation and hyperphosphorylation is a key neuropathological hallmark of Alzheimer's disease (AD), and the temporospatial spread of Tau observed during clinical manifestation suggests that Tau pathology may spread along the axonal network and propagate between synaptically connected neur...
Guardat en:
| Publicat a: | J Biol Chem |
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| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7489902/ https://ncbi.nlm.nih.gov/pubmed/32699110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013325 |
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