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Bayesian Physics-Based Modeling of Tau Propagation in Alzheimer's Disease

Amyloid-β and hyperphosphorylated tau protein are known drivers of neuropathology in Alzheimer's disease. Tau in particular spreads in the brains of patients following a spatiotemporal pattern that is highly sterotypical and correlated with subsequent neurodegeneration. Novel medical imaging te...

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Udgivet i:Front Physiol
Main Authors: Schäfer, Amelie, Peirlinck, Mathias, Linka, Kevin, Kuhl, Ellen
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8322942/
https://ncbi.nlm.nih.gov/pubmed/34335308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.702975
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