Accounting for the Delay in the Transition from Acute to Chronic Pain: Axonal and Nuclear Mechanisms

Acute insults produce hyperalgesic priming, a neuroplastic change in nociceptors that markedly prolongs inflammatory mediator-induced hyperalgesia. After an acute initiating insult, there is a 72 h delay to the onset of priming, for which the underlying mechanism is unknown. We hypothesized that the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Ferrari, Luiz F., Bogen, Oliver, Reichling, David B., Levine, Jon D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2015
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293406/
https://ncbi.nlm.nih.gov/pubmed/25589745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5147-13.2015
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