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Accounting for the Delay in the Transition from Acute to Chronic Pain: Axonal and Nuclear Mechanisms
Acute insults produce hyperalgesic priming, a neuroplastic change in nociceptors that markedly prolongs inflammatory mediator-induced hyperalgesia. After an acute initiating insult, there is a 72 h delay to the onset of priming, for which the underlying mechanism is unknown. We hypothesized that the...
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| Veröffentlicht in: | J Neurosci |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4293406/ https://ncbi.nlm.nih.gov/pubmed/25589745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5147-13.2015 |
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