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Peripheral Administration of Translation Inhibitors Reverses Increased Hyperalgesia in a Model of Chronic Pain in the Rat

Chronic pain is extremely difficult to manage, in part due to lack of progress in reversing the underlying pathophysiology. Since translation of mRNAs in the peripheral terminal of the nociceptor plays a role in the transition from acute to chronic pain, we tested the hypothesis that transient inhib...

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Detalhes bibliográficos
Main Authors: Ferrari, Luiz F., Bogen, Oliver, Chu, Carissa, Levine, Jon D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700567/
https://ncbi.nlm.nih.gov/pubmed/23664545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2013.01.779
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