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Role of Nociceptor αCaMKII in Transition from Acute to Chronic Pain (Hyperalgesic Priming) in Male and Female Rats

We have previously shown that activation of protein kinase Cε (PKCε) in male rats induces a chronic, long-lasting change in nociceptors such that a subsequent exposure to proinflammatory mediators produces markedly prolonged mechanical hyperalgesia. This neuroplastic change, hyperalgesic priming, is...

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Detalhes bibliográficos
Main Authors: Ferrari, Luiz F., Bogen, Oliver, Levine, Jon D.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718370/
https://ncbi.nlm.nih.gov/pubmed/23825405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1785-13.2013
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