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Hyperalgesic Priming is Restricted to IB4-positive Nociceptors

We have previously described a rat model for the contribution of neuroplastic changes in nociceptors to the transition from acute to chronic pain. In this model a prior injury activates protein kinase C epsilon (PKCε), inducing a chronic state characterized by marked prolongation of the hyperalgesia...

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Hlavní autoři: Joseph, Elizabeth K., Levine, Jon D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903040/
https://ncbi.nlm.nih.gov/pubmed/20457222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.04.082
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