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Opioid-Induced Hyperalgesic Priming in Single Nociceptors
Clinical µ-opioid receptor (MOR) agonists produce hyperalgesic priming, a form of maladaptive nociceptor neuroplasticity, resulting in pain chronification. We have established an in vitro model of opioid-induced hyperalgesic priming (OIHP), in male rats, to identify nociceptor populations involved a...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7786210/ https://ncbi.nlm.nih.gov/pubmed/33203743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2160-20.2020 |
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