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Hyperalgesic Priming (Type II) Induced by Repeated Opioid Exposure: Maintenance Mechanisms

We previously developed a model of opioid-induced neuroplasticity in the peripheral terminal of the nociceptor that could contribute to opioid-induced hyperalgesia, type II hyperalgesic priming. Repeated administration of mu-opioid receptor (MOR) agonists, such as DAMGO, at the peripheral terminal o...

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Detalhes bibliográficos
Publicado no:Pain
Main Authors: Araldi, Dioneia, Ferrari, Luiz F., Levine, Jon D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474187/
https://ncbi.nlm.nih.gov/pubmed/28306605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000898
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