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Shared Mechanisms for Opioid Tolerance and a Transition to Chronic Pain

Clinical pain conditions may remain responsive to opiate analgesics for extended periods, but such persistent acute pain can undergo a transition to an opiate-resistant chronic pain state that becomes a much more serious clinical problem. To test the hypothesis that cellular mechanisms of chronic pa...

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Detalhes bibliográficos
Main Authors: Joseph, Elizabeth K., Reichling, David B., Levine, Jon D.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857996/
https://ncbi.nlm.nih.gov/pubmed/20357116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5530-09.2010
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