Ring-Opening Polymerization of Prodrugs: A Versatile Approach to Prepare Well-Defined Drug Loaded Nanoparticles**

We report a new methodology for the synthesis of polymer-drug conjugates from “compound”—all in one—prodrug monomers that consist of a cyclic polymerizable group that is appended to a drug through a cleavable linker. We show that organocatalyzed ring-opening polymerization can polymerize these monom...

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Detaylı Bibliyografya
Yayımlandı:Angew Chem Int Ed Engl
Asıl Yazarlar: Liu, Jinyao, Liu, Wenge, Weitzhandler, Isaac, Bhattacharyya, Jayanta, Li, Xinghai, Wang, Jing, Qi, Yizhi, Bhattacharjee, Somnath, Chilkoti, Ashutosh
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293338/
https://ncbi.nlm.nih.gov/pubmed/25427831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201409293
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