Cargando...

Incorporation of ABCB1-mediated transport into a physiologically-based pharmacokinetic model of docetaxel in mice

Docetaxel is one of the most widely used anticancer agents. While this taxane has proven to be an effective chemotherapeutic drug, noteworthy challenges exist in relation to docetaxel administration due to the considerable interindividual variability in efficacy and toxicity associated with the use...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Pharmacokinet Pharmacodyn
Main Authors: Hudachek, Susan F., Gustafson, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292804/
https://ncbi.nlm.nih.gov/pubmed/23616082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-013-9317-1
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!