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Incorporation of ABCB1-mediated transport into a physiologically-based pharmacokinetic model of docetaxel in mice

Docetaxel is one of the most widely used anticancer agents. While this taxane has proven to be an effective chemotherapeutic drug, noteworthy challenges exist in relation to docetaxel administration due to the considerable interindividual variability in efficacy and toxicity associated with the use...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Pharmacokinet Pharmacodyn
Egile Nagusiak: Hudachek, Susan F., Gustafson, Daniel L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292804/
https://ncbi.nlm.nih.gov/pubmed/23616082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-013-9317-1
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