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Incorporation of ABCB1-mediated transport into a physiologically-based pharmacokinetic model of docetaxel in mice
Docetaxel is one of the most widely used anticancer agents. While this taxane has proven to be an effective chemotherapeutic drug, noteworthy challenges exist in relation to docetaxel administration due to the considerable interindividual variability in efficacy and toxicity associated with the use...
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| 發表在: | J Pharmacokinet Pharmacodyn |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4292804/ https://ncbi.nlm.nih.gov/pubmed/23616082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-013-9317-1 |
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