Dendritic cell-derived interleukin-15 is crucial for therapeutic cancer vaccine potency

IL-15 supports improved antitumor immunity. How to best incorporate IL-15 into vaccine formulations for superior cancer immunotherapy remains a challenge. DC-derived IL-15 (DCIL-15) notably has the capacity to activate DC, to substitute for CD4(+) Th and to potentiate vaccine efficacy making IL-15-b...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Zhang, Yi, Tian, Shenghe, Liu, Zuqiang, Zhang, Jiying, Zhang, Meili, Bosenberg, Marcus W, Kedl, Ross M, Waldmann, Thomas A, Storkus, Walter J, Falo, Louis D, You, Zhaoyang
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2014
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292719/
https://ncbi.nlm.nih.gov/pubmed/25941586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.959321
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