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Genetic Targeting of the Active Transcription Factor XBP1s to Dendritic Cells Potentiates Vaccine-induced Prophylactic and Therapeutic Antitumor Immunity
In vivo dendritic cells (DC) targeting is an attractive approach with potential advantages in vaccine efficacy, cost, and availability. Identification of molecular adjuvants to in vivo “modulate ” DC to coordinately render improved Th1 and CD8 T cell immunity, and attenuated deleterious Treg effects...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3277233/ https://ncbi.nlm.nih.gov/pubmed/21934655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.183 |
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