Therapeutic Immunity by Adoptive Tumor-primed CD4(+) T-cell Transfer in Combination With In Vivo GITR Ligation

Tumor-primed CD4(+) T cells from splenocytes of tumor-rejection mice in combination with in vivo glucocorticoid-induced tumor necrosis factor receptor (GITR) ligation (the combination therapy) elicited effective host CD8(+) T cell–dependent therapeutic immunity against a murine breast tumor. GITR li...

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Bibliographic Details
Main Authors: Liu, Zuqiang, Tian, Shenghe, Falo, Louis D, Sakaguchi, Shimon, You, Zhaoyang
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2009
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731416/
https://ncbi.nlm.nih.gov/pubmed/19417739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.100
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