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Tumor Regulatory T Cells Potently Abrogate Antitumor Immunity

Treg from mice bearing a breast tumor were elevated (tumor Treg). In vitro, whereas tumor Treg ability to inhibit tumor-primed CD4(+) T cell activity is comparable to Treg from naïve mice (naïve Treg), only tumor Treg suppress naïve CD8(+) T cell activation and DC function. Neither tumor Treg nor na...

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Sonraí Bibleagrafaíochta
Main Authors: Liu, Zuqiang, Kim, Jin H., Falo, Louis D., You, Zhaoyang
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731421/
https://ncbi.nlm.nih.gov/pubmed/19414769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802664
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