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Genetic Targeting of the Active Transcription Factor XBP1s to Dendritic Cells Potentiates Vaccine-induced Prophylactic and Therapeutic Antitumor Immunity

In vivo dendritic cells (DC) targeting is an attractive approach with potential advantages in vaccine efficacy, cost, and availability. Identification of molecular adjuvants to in vivo “modulate ” DC to coordinately render improved Th1 and CD8 T cell immunity, and attenuated deleterious Treg effects...

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Detaylı Bibliyografya
Asıl Yazarlar: Tian, Shenghe, Liu, Zuqiang, Donahue, Cara, Falo, Louis D, You, Zhaoyang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277233/
https://ncbi.nlm.nih.gov/pubmed/21934655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.183
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