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Utilising Family-Based Designs for Detecting Rare Variant Disease Associations
Rare genetic variants are thought to be important components in the causality of many diseases but discovering these associations is challenging. We demonstrate how best to use family-based designs to improve the power to detect rare variant disease associations. We show that using genetic data from...
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| Publicado no: | Ann Hum Genet |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4292528/ https://ncbi.nlm.nih.gov/pubmed/24571231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ahg.12051 |
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