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Rare Variant Analysis for Family-Based Design

Genome-wide association studies have been able to identify disease associations with many common variants; however most of the estimated genetic contribution explained by these variants appears to be very modest. Rare variants are thought to have larger effect sizes compared to common SNPs but effec...

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Hlavní autoři: De, Gourab, Yip, Wai-Ki, Ionita-Laza, Iuliana, Laird, Nan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546113/
https://ncbi.nlm.nih.gov/pubmed/23341868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048495
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