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Rare Variant Analysis for Family-Based Design

Genome-wide association studies have been able to identify disease associations with many common variants; however most of the estimated genetic contribution explained by these variants appears to be very modest. Rare variants are thought to have larger effect sizes compared to common SNPs but effec...

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Detalhes bibliográficos
Main Authors: De, Gourab, Yip, Wai-Ki, Ionita-Laza, Iuliana, Laird, Nan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546113/
https://ncbi.nlm.nih.gov/pubmed/23341868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048495
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