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Study Designs for Identification of Rare Disease Variants in Complex Diseases: The Utility of Family-Based Designs
The recent progress in sequencing technologies makes possible large-scale medical sequencing efforts to assess the importance of rare variants in complex diseases. The results of such efforts depend heavily on the use of efficient study designs and analytical methods. We introduce here a unified fra...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3213373/ https://ncbi.nlm.nih.gov/pubmed/21840850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.131813 |
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