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Study Designs for Identification of Rare Disease Variants in Complex Diseases: The Utility of Family-Based Designs

The recent progress in sequencing technologies makes possible large-scale medical sequencing efforts to assess the importance of rare variants in complex diseases. The results of such efforts depend heavily on the use of efficient study designs and analytical methods. We introduce here a unified fra...

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Bibliografische gegevens
Hoofdauteurs: Ionita-Laza, Iuliana, Ottman, Ruth
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Genetics Society of America 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213373/
https://ncbi.nlm.nih.gov/pubmed/21840850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.131813
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