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A New Testing Strategy to Identify Rare Variants with Either Risk or Protective Effect on Disease
Rapid advances in sequencing technologies set the stage for the large-scale medical sequencing efforts to be performed in the near future, with the goal of assessing the importance of rare variants in complex diseases. The discovery of new disease susceptibility genes requires powerful statistical m...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033379/ https://ncbi.nlm.nih.gov/pubmed/21304886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001289 |
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