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Population-based and Family-based Designs to Analyze Rare Variants in Complex Diseases
Genotyping of rare variants on a large scale is now possible using next-generation sequencing. The sample selection is a crucial step in designing the genetic study of a complex disease and knowledge of the efficiency and limitations of the population-based and family-based designs can help making t...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3393851/ https://ncbi.nlm.nih.gov/pubmed/22128057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20648 |
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