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Identifying causal rare variants of disease through family-based analysis of Genetics Analysis Workshop 17 data set

Linkage- and association-based methods have been proposed for mapping disease-causing rare variants. Based on the family information provided in the Genetic Analysis Workshop 17 data set, we formulate a two-pronged approach that combines both methods. Using the identity-by-descent information provid...

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Detalhes bibliográficos
Main Authors: Yip, Wai-Ki, De, Gourab, Raby, Benjamin A, Laird, Nan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287856/
https://ncbi.nlm.nih.gov/pubmed/22373204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S21
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