Evaluation of association tests for rare variants using simulated data sets in the Genetic Analysis Workshop 17 data

We evaluate four association tests for rare variants—the combined multivariate and collapsing (CMC) method, two weighted-sum methods, and a variable threshold method—by applying them to the simulated data sets of unrelated individuals in the Genetic Analysis Workshop 17 (GAW17) data. The family-wise...

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Detalhes bibliográficos
Main Authors: Chen, Wenan, Gao, Xi, Wang, Jiexun, Sun, Chuanyu, Wan, Wen, Zhi, Degui, Liu, Nianjun, Chen, Xiangning, Gao, Guimin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Proceedings
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287927/
https://ncbi.nlm.nih.gov/pubmed/22373475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S86
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