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Evaluation of association tests for rare variants using simulated data sets in the Genetic Analysis Workshop 17 data

We evaluate four association tests for rare variants—the combined multivariate and collapsing (CMC) method, two weighted-sum methods, and a variable threshold method—by applying them to the simulated data sets of unrelated individuals in the Genetic Analysis Workshop 17 (GAW17) data. The family-wise...

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Bibliografiske detaljer
Main Authors: Chen, Wenan, Gao, Xi, Wang, Jiexun, Sun, Chuanyu, Wan, Wen, Zhi, Degui, Liu, Nianjun, Chen, Xiangning, Gao, Guimin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287927/
https://ncbi.nlm.nih.gov/pubmed/22373475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S86
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