Improved Methods for Production, Isolation, and Assay of Two New Chloroisoxazoline Amino Acid Antitumor Antimetabolites: U-42,126 and U-43,795
Improved fermentation and isolation procedures for antitumor antimetabolites U-42,126 and U-43,795 increased drug yields 30-fold. The sensitivity limit of a newly developed assay is 0.03 μg of U-42,126 and 2.0 μg of U-43,795 per ml. The in vitro antimicrobial effect of both drugs was antagonized by...
Gorde:
| Argitaratua izan da: | Antimicrob Agents Chemother |
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| Egile Nagusiak: | , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Microbiology (ASM)
1975
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429230/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1155921/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.7.6.807 |
| Etiketak: |
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