Synthesis and Structure–Activity Relationship Study of 5a-Carbasugar Analogues of SL0101

[Image: see text] The Ser/Thr protein kinase, RSK, is associated with oncogenesis, and therefore, there are ongoing efforts to develop RSK inhibitors that are suitable for use in vivo. SL0101 is a natural product that demonstrates selectivity for RSK inhibition. However, SL0101 has a short biologica...

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書誌詳細
出版年:ACS Med Chem Lett
主要な著者: Li, Mingzong, Li, Yu, Mrozowski, Roman M., Sandusky, Zachary M., Shan, Mingde, Song, Xiwen, Wu, Bulan, Zhang, Qi, Lannigan, Deborah A., O’Doherty, George A.
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2014
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291707/
https://ncbi.nlm.nih.gov/pubmed/25589938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml5004525
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