MD-2 is required for disulfide HMGB1–dependent TLR4 signaling

Innate immune receptors for pathogen- and damage-associated molecular patterns (PAMPs and DAMPs) orchestrate inflammatory responses to infection and injury. Secreted by activated immune cells or passively released by damaged cells, HMGB1 is subjected to redox modification that distinctly influences...

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Detaylı Bibliyografya
Yayımlandı:J Exp Med
Asıl Yazarlar: Yang, Huan, Wang, Haichao, Ju, Zhongliang, Ragab, Ahmed A., Lundbäck, Peter, Long, Wei, Valdes-Ferrer, Sergio I., He, Mingzhu, Pribis, John P., Li, Jianhua, Lu, Ben, Gero, Domokos, Szabo, Csaba, Antoine, Daniel J., Harris, Helena E., Golenbock, Doug T., Meng, Jianmin, Roth, Jesse, Chavan, Sangeeta S., Andersson, Ulf, Billiar, Timothy R., Tracey, Kevin J., Al-Abed, Yousef
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2015
Konular:
Brief Definitive Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291531/
https://ncbi.nlm.nih.gov/pubmed/25559892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20141318
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