Epidermal growth factor-receptor mutant lacking the autophosphorylation sites induces phosphorylation of Shc protein and Shc-Grb2/ASH association and retains mitogenic activity.

Epidermal growth factor (EGF) receptor (EGFR) can induce cell growth and transformation in a ligand-dependent manner. To examine whether the autophosphorylation of EGFR correlates with the capacity of the activated EGFR to induce cell growth and transformation, we truncated the human EGFR just after...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gotoh, N, Tojo, A, Muroya, K, Hashimoto, Y, Hattori, S, Nakamura, S, Takenawa, T, Yazaki, Y, Shibuya, M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1994
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC42907/
https://ncbi.nlm.nih.gov/pubmed/7506413
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