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Epidermal growth factor-receptor mutant lacking the autophosphorylation sites induces phosphorylation of Shc protein and Shc-Grb2/ASH association and retains mitogenic activity.

Epidermal growth factor (EGF) receptor (EGFR) can induce cell growth and transformation in a ligand-dependent manner. To examine whether the autophosphorylation of EGFR correlates with the capacity of the activated EGFR to induce cell growth and transformation, we truncated the human EGFR just after...

詳細記述

保存先:
書誌詳細
主要な著者: Gotoh, N, Tojo, A, Muroya, K, Hashimoto, Y, Hattori, S, Nakamura, S, Takenawa, T, Yazaki, Y, Shibuya, M
フォーマット: Artigo
言語:Inglês
出版事項: 1994
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC42907/
https://ncbi.nlm.nih.gov/pubmed/7506413
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