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Inhibition of [(14)C]Chloramphenicol Binding to Escherichia coli Ribosomes by Erythromycin Derivatives

The effect of erythromycin A and 35 analogues of erythromycin A on [(14)C]chloramphenicol binding to Escherichia coli ribosomes was evaluated. Substitutions on various portions of the erythromycin molecule were made with retention of ability to bind to ribosomes. Specifically, substantial activity i...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Pestka, Sidney, LeMahieu, Ronald A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1974
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429045/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15828169/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.6.1.39
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