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Correlation of Effects of Erythromycin Analogues on Intact Bacteria and on [(14)C]Erythromycin Binding to Escherichia coli Ribosomes

The dissociation constants for binding to ribosomes from Escherichia coli and concentrations at which 50% inhibition of [(14)C]erythromycin binding to ribosomes occurred were determined for 45 erythromycin analogues. These values were correlated with their antibacterial activities against Bacillus s...

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Detalhes bibliográficos
Main Authors: Pestka, Sidney, Lemahieu, Ronald, Miller, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC444676/
https://ncbi.nlm.nih.gov/pubmed/4157350
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